產(chǎn)品簡介：

• 僅使用一個傳感器對O2和CO2 進行平行、持續(xù)性的測量

•  

• 標(biāo)準(zhǔn)化地集成至T&J-生物反應(yīng)器，用于通過呼吸參數(shù)的實時測定來實現(xiàn)基于事件的控制操作。

•  

• 自動補償濕度和壓力功能確保了高精度和工藝可靠性

•  

• 緊湊的設(shè)計使其能方便地集成至小型實驗室生物反應(yīng)器或工藝規(guī)模地發(fā)酵罐

•  

• 在BioPAT-gasbox 上直接有標(biāo)準(zhǔn)顯示屏和校準(zhǔn)按鈕，操作簡便

產(chǎn)品特性：

T&J-gasbox 由具有自動補償濕度和壓力功能的O₂ |. CO₂傳感器組成，用于持續(xù)性的監(jiān)測并控制生物工藝。排出的尾氣經(jīng)過集成的流量適配器進入測試腔，并在此進行O₂ 和CO₂ 水平、濕度和壓力的分析。

      由  T&J-gasbox測量的氧氣和二氧化碳的變化值為生物量、基質(zhì)消耗以及產(chǎn)品形成速率提供了實時數(shù)據(jù)。通過質(zhì)量流量控制器精確測量進氣中的氧氣和二氧化碳濃度，然后減去由  T&J-gasbox 測得的排氣中的測量值，計算獲得實時數(shù)據(jù)。可以計算的標(biāo)準(zhǔn)參數(shù)如下：

• 氧氣攝入率 (OUR)

• 二氧化碳排放速率 / 二氧化碳生產(chǎn)速率 (CER / CPR)

•呼吸商 (RQ)

用于優(yōu)化的工藝控制排氣分析的PAT組合常通過微生物發(fā)酵和高細胞密度的培養(yǎng)來進行，因為這兩種工藝都具有高耗氧量和高二氧化碳生產(chǎn)速度的特點。它可自動計算標(biāo)準(zhǔn)參數(shù)，允許通過自動進料策略或階段變化來執(zhí)行控制回路。這一組合為實施完整的PAT概念用以增強生物工藝控制提供了額外的步驟。

Start QbD with the  T&J-gasbox units

      In modern bioprocessing Quality by Design (QbD) is becoming more and more a standard. That means that you always have to know and to understand your complete process and key parameters during the complete production process. To understand and to document your process during the complete production process makes modern bioprocessing save and guarantees highest quality. With the  gas analyzers each individual process is comprehensively analyzed and documented independently. The gasbox series makes it easy for you to start with the QbD production right away. When measurements are made using several   T&J-gasbox units, all analyzers can be conveniently read out and controlled by just one computer. Contemporary bioprocessing frequently involves performing several processes in parallel. Specific variations can be tested in the individual bioreactors under identical c*tion conditions, allowing the decisive factors to be determined much faster (design of experiments, DOE). To start the QbD production, each gasbox only measures one process, allowing a very large amount of data to be obtained  continuously and without interruptions, and practically eliminating the risk of inter-process contamination (this risk cannot be eliminated with a central analyzer). At an industrial scale, parallel processes make a continual production flow possible. If a fermenter is shut down for maintenance purposes, the remaining bioreactors can continue their production without problems. Using a central analyzer (mass spectrometer) for all fermenters would mean that you rely on a single device that could stop the complete production process. With the gas analyzers each individual process is comprehensively analyzed and documented independently. The gasbox series makes it easy for you to start with the QbD production. 

 技術(shù)參數(shù)：

Bacteria測試范圍：O₂: 1-50%; CO₂測試范圍：0 - 10%;

Cell測試范圍：O₂: 1-*; CO₂測試范圍：0 - 25%;

濕度范圍：0 - *

單點校準(zhǔn)：20.97%

O2; 0.04% CO2)

壓力范圍：0.8-1.3 bar

箱子： 不銹鋼，IP65

溫度范圍：15 - 40 ° C